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Current Grant Support

Exploiting sex-dependent brain injury responses for nanoparticle therapeutics (R01)

Project duration: 01/01/2021 - 12/31/2026

Sponsor: The National Institutes of Health, NINDS

MPI: Stabenfeldt/Sirianni

Intrathecal delivery of radiation sensitizing nanoparticles (R01)

Project duration: 07/01/2019 – 06/31/2024

Sponsor: The National Institutes of Health, NICHD

PI: Sirianni


Targeting leptomeningeal metastasis in medulloblastoma (R01)

Project duration: 05/01/2019 – 04/30/2024

Sponsor: National Institutes of Health, NINDS

PI: Sirianni

Inhibiting metastasis and preventing recurrence in MYC-amplified medulloblastoma

Project duration: 05/01/2020 - 04/31/2023

Sponsor: The Matthew Larson Foundation

Role: co-I (PI, Yanxin Pei)

 Past Grant Support

Biomimetic microenvironments to model leptomeningeal metastasis in pediatric neuro-oncology

Project duration: 03/01/2019 – 02/28/2020

Sponsor: The Morgan Adams Foundation

PI: Sirianni


Nanotherapeutics to alleviate neuroinflammation after TBI (R21)

Project duration: 7/1/2018 – 6/30/2020 (through 2021 under NCE)

Sponsor: National Institutes of Health, NINDS

MPI: Stabenfeldt/Sirianni


Faculty Science and Technology Acquisition and Retention (STARs) Award

Project duration: 7/1/2018-6/31/2020

Sponsor: The University of Texas Health Science Center at Houston

PI: Sirianni


Intra-CSF delivery of targeted nanoparticles to treat leptomeningeal metastasis

Project duration: 7/18/2018-7/17/2019

Sponsor: Ian’s Friends Foundation

PI: Sirianni

Detecting and treating traumatic brain injury pathology progression from the inside-out – Supplement for AD/ADRD research (DP2)

Project duration: 9/11/2018 – 6/30/2019

Sponsor: National Institutes of Health, NICHD/NIA

PI: Stabenfeldt (co-I: Sirianni)


Central nervous system targeted drug delivery 
Project duration: 7/1/2017-6/30/2019
Sponsor: 2016 Women’s Board Project (Barrow Neurological Foundation)
PI: Sirianni


Pathogen-Inspired Nanoparticle Drug Delivery to Motor Neurons

Project duration: 8/5/2014 – 8/4/2016

Sponsor: Department of Defense, CDMRP

PI: Sirianni


Nanotechnology to treat glioblastoma

Project duration: 7/1/2014 – 6/7/2018

Sponsor: The Rick Oehme Foundation

PI: Sirianni


Expanding Therapeutic Options for Glioblastoma

Subaward: Delivery of drugs across the blood brain barrier

Project duration: 11/1/2013 – 12/31/2015

Sponsor: The Ben and Catherine Ivy Foundation

PI: Michael Berens (subaward PI: Sirianni)

Support for Trainees


Modulating retinoid signaling as a therapeutic approach for ALS

Project duration: 8/1/2015-7/31/2017

Sponsor: The ALS Association

Recipient: David Medina, Ph.D.


Development of targeted delivery of estrogen to examine its effect on cognitive function (NSF GRF)

Project duration: 6/1/2014-5/31/2017

Sponsor: National Science Foundation

Recipient: Alesia Prakapenka

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